Patients with 47, XXX karyotype who experienced premature ovarian failure (POF): two case reports
نویسندگان
چکیده
منابع مشابه
A case of premature ovarian failure (POF) in a 31-year-old woman with a 47,XXX karyotype.
A case of POF in a 31-year-old woman with karyotype 47,XXX. The aim of the study was to discuss a case of POF in a 31-year-old patient with polysomy 47,XXX. The described karyotype is not usually associated with this characteristic physical phenotype. In some rare cases, menstrual disorders, sterility, secondary amenorrhoea, premature menopause, and low intelligence are found. Our observations ...
متن کاملFemale-to-male transsexual with 47,XXX karyotype.
BACKGROUND There are few reports describing chromosomal abnormalities in transsexuals. In rare cases, transsexualism and sexual chromosomal multiplicity coexist. Six cases of male-to-female transsexuals with 47,XYY chromosomal pattern have been previously reported. We have not encountered any female transsexual cases with 47,XXX karyotype in the literature. METHODS A 21-year-old female patien...
متن کاملI-41: Genetic Causes of Premature Ovarian Failure (POF) and early Menopause
Premature ovarian failure (POF) is a heterogeneous disorder, defined as menopause under age 40 years. The prevalence is 1%; POF before age 30 years is much less common. Chromosomal causes have long been recognized - visible deletions of the X chromosome, 45,X/46,XX mosaicism, and autosomal rearrangements (balanced translocations). Toxins or iatrogenic causes (e.g., chemotherapeutic agents) are ...
متن کاملBeneficial Effects of Tibolone on Sexual Dysfunction in Women with Premature Ovarian Failure (POF)
Introduction: Premature Ovarian Failure (POF) is cessation of ovarian functions before the age of 40 years old with consequent cessation of menstruation. Objective of study: The aim of this study was to evaluate the association between Premature Ovarian Failure and sexual dysfunctions and outcome of management with tibolone. Patients and Methods: Thirty-one women with Premature Ovarian Failure ...
متن کاملChromosomal abnormalities & oxidative stress in women with premature ovarian failure (POF)
BACKGROUND & OBJECTIVES Premature ovarian failure (POF) is defined as the cessation of ovarian function under the age of 40 yr and is characterized by amenorrhoea, hypoestrogenism and elevated serum gonadotrophin levels. The cause of POF remains undetermined in majority of the cases. This study was aimed to investigate the type and frequency of cytogenetic abnormalities in patients with idiopat...
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ژورنال
عنوان ژورنال: Reproductive Medicine and Biology
سال: 2013
ISSN: 1445-5781
DOI: 10.1007/s12522-013-0158-9